|
Resolution: standard / high Figure 1.
9-cis RA blocks effects of CAR ligands on coactivator binding in vitro. GST-SRC-3 fusion protein was immobilized on a flow cell and tested for interaction
with receptors. A. Overlaid results of injections of apo-RXR and RXR preincubated in the presence of
9-cis RA. B. Overlaid results of injections of apo-CAR and CAR preincubated in the presence of
TCPOBOP (TC) or androstanol (An). C. Overlaid results of injections of preformed CAR/RXR heterodimers preincubated in the
presence or absence of 9-cis RA and TCPOBOP (TC) as indicated. D. Overlaid results of injections of preformed CAR/RXR heterodimers preincubated in the
presence or absence of 9-cis RA and androstanol (An) as indicated.
Tzameli et al. Nuclear Receptor 2003 1:2 doi:10.1186/1478-1336-1-2 |
